Usually considered as the antimicrobial enzyme supplement, Lactoperoxidase is to be found in the saliva, tears, and milk of only mammals. Apart from these, you can also find this supplement in colostrum and whey. This supplement is also known for contributing as the defense system of a nonimmune host. By acting as the defense system, the lactoperoxidase supplement happens to exert certain bactericidal activities. This activity is mostly seen taking place on bacterias that are gram-negative like Salmonella, E. coli, as well as Pseudomonas.
Understanding the mechanism of Lactoperoxidase
The lactoperoxidase activity in milk owes to some other activities as well. It happens to promote growth activity as well as the antitumor activity to a large extent. These activities can prove to be great benefits to human beings. Having said that, the lactoperoxidase supplement keeps a quite close relation, almost 71%, to thyroid peroxidase of humans. This is further involved in coupling and iodination in the thyroid hormone formation.
The lactoperoxidase supplement is biologically extremely significant because of its ability to act as the host defense mechanism against bacteria. It is also very much possible to isolate this supplement from whey simply because the supplement remains charged positively. It has been widely studied that Lactoperoxidase supplement is capable of inhibiting the growth of a variety of microorganisms. This growth can be initiated usually through a reaction of enzymes, involving the cofactor ions of thiocyanate and H2O2. Altogether, these ions constitute the system of lactoperoxidase. The viability, as well as the growth of bacteria, has suffered a great reduction because of this system.
Effect Of The Lactoproxidase Supplement
The tablets containing the lactoperoxidase supplement is known for treating individuals who are greatly suffering from chronic periodontitis. These tablets are to be consumed orally and thus, helps in either the control or the eradication of the periodontopathic bacteria. This supplement is generally a family member of peroxidase with mammalian heme. The tablets that contain the Lactoperoxidase supplement happens to exhibit certain inhibitory effects. These effects are basically on the bacterias found in oral malodor and saliva.
This supplement happens to owe a lot to oral health and holds quite a huge significance. This contains both iron-based and calcium-based glycoprotein. The calcium ion generally plays a pretty significant role in maintaining both the enzymes’ stability. The formation of this supplement is quite complex to understand. This is undoubtedly an extremely important milk enzyme that contributes to the vitality of human health and nutrition. A life that includes enzymes, immunoglobulins, hormones, minerals, vitamins, growth factors, and antibacterial agents is much positively affected by Lactoperoxidase.
This natural constituent is present in all sorts of mammary milk and its molecular weight happens to be around 78 kDa. Like the Immunoglobulin G, lactoperoxidase supplement exists in mammals such as human beings, cow, goat, bovine, sheep, mice milk, camel, llama, lachrymal glands, and buffalo. Its most important function still happens to be also chemically involved in catalyzing the thiocyanate oxidation process as well.